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BCRJ:	0319
Cell Line:	MDA-MB-157
Tissue:	MEDULLA
Organ:	MAMARIAN GLAND
Cell Type:	EPITHELIAL
Morphology:	EPITHELIAL
Pathology:
Scientific Name:	HOMO SAPIENS
Vulgar Name:	HUMAN
Sex:	FEMALE
Miscelaneous Info:	44 YEARS ADULT
Virus Succeptibility:
Virus Resistance:
Tumor Formation:	YES, IN NUDE MICE AND IN IMMUNOSUPPRESSED
Products:
Dependency Isoenzymes:	AK-1, 1; ES-D, 1; G6PD, B; GLO-I, 2; PGM1, 1; PGM3, 1; Me-2,1.
Culture Medium:	LEIBOVITZ + 10% FETAL BOVINE SERUM
Consigner:	RENATO J. S OLIVEIRA (CPOM) - HOSPITAL DE CÂNCER DE BARRETOS
Reference:	"Brinkley BR, et al. Variations in cell form and cytoskeleton in human breast carcinoma cells in vitro. Cancer Res. 40: 3118-3129, 1980; Cruciger Q, et al. Morphological, biochemical and chromosomal characterization of breast tumor lines from pleural effusions. In Vitro 12: 331, 1976.; Young RK, et al. Establishment of epithelial cell line MDA-MB-157 from metastatic pleural effusion of human breast carcinoma. In Vitro 9: 239-245, 1974.; Siciliano MJ, et al. Mutually exclusive genetic signatures of human breast tumor cell lines with a common chromosomal marker. Cancer Res. 39: 919-922, 1979. ; Cailleau R, et al. Breast tumor cell lines from pleural effusions. J. Natl. Cancer Inst. 53: 661-674, 1974. PubMed: 4412247 22656: Cailleau R, et al. Long-term human breast carcinoma cell lines of metastatic origin: preliminary characterization. In Vitro 14: 911-915, 1978. "
Additional Info:	" The cells express the WNT7B oncogene [PubMed: 8168088]. The method for derivation of this line was similar in detail to that for ATCC HTB-23. Desmosomes, microvilli and tonofilaments were observed at boundaries between cells."
ATCC:	HTB-24
Biosafety:	1