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BCRJ: 0303
Cell Line: NTERA-2 cl.D1 [NT2/D1]
Tissue: TESTIS
Organ: TETIS
Cell Type: EPITHELIAL-LIKE
Morphology: EPITHELIAL-LIKE
Pathology: MALIGNANT PLURIPOTENT EMBRYONAL CARCINOMA
Scientific Name: HOMO SAPIENS
Vulgar Name: HUMAN
Sex: MALE
Miscelaneous Info: 22 YEARS
Virus Succeptibility: RA AND HMBA TREATED CELLS: HUMAN CYTOMEGALOVIRUS; HUMAN IMMUNODEFICIENCY VIRUS (HIV, HTLV-III)
Virus Resistance:
Tumor Formation:
Products:
Dependency Isoenzymes:
Culture Medium: Dulbecco’s modified Eagle’s medium with 10% fetal bovine serum
Consigner: CATARINA SEGRETI PORTO - Instituto de Farmacologia - INFAR
Reference: "Andrews PW. Human teratocarcinomas. Biochim. Biophys. Acta 948: 17-36, 1988. PubMed: 3293662 22336: Mavilio F, et al. Activation of four homeobox gene clusters in human embryonal carcinoma cells induced to differentiate by retinoic acid. Differentiation 37: 73-79, 1988. PubMed: 2898410 22407: Fenderson BA, et al. Glycolipid core structure switching from globo- to lacto- and ganglio- series during retinoic acid-induced differentiation of TERA-2-derived human embryonal carcinoma cells. Dev. Biol. 122: 21-34, 1987. PubMed: 3297853 22741: Andrews PW, et al. Pluripotent embryonal carcinoma clones derived from the human teratocarcinoma cell line Tera-2. Differentiation in vivo and in vitro. Lab. Invest. 50: 147-162, 1984. PubMed: 6694356 22746: Andrews PW, et al. Different patterns of glycolipid antigens are expressed following differentiation of TERA-2 human embryonal carcinoma cells induced by retinoic acid, hexamethylene bisacetamide (HMBA) or bromodeoxyuridine (BUdR). Differentiation 43: 131-138, 1990. PubMed: 2373286 Andrews PW. Human teratocarcinomas. Biochim. Biophys. Acta 948: 17-36, 1988. PubMed: 3293662 22336: Mavilio F, et al. Activation of four homeobox gene clusters in human embryonal carcinoma cells induced to differentiate by retinoic acid. Differentiation 37: 73-79, 1988. PubMed: 2898410 22407: Fenderson BA, et al. Glycolipid core structure switching from globo- to lacto- and ganglio- series during retinoic acid-induced differentiation of TERA-2-derived human embryonal carcinoma cells. Dev. Biol. 122: 21-34, 1987. PubMed: 3297853 22741: Andrews PW, et al. Pluripotent embryonal carcinoma clones derived from the human teratocarcinoma cell line Tera-2. Differentiation in vivo and in vitro. Lab. Invest. 50: 147-162, 1984. PubMed: 6694356 22746: Andrews PW, et al. Different patterns of glycolipid antigens are expressed following differentiation of TERA-2 human embryonal carcinoma cells induced by retinoic acid, hexamethylene bisacetamide (HMBA) or bromodeoxyuridine (BUdR). Differentiation 43: 131-138, 1990. PubMed: 2373286 "
Additional Info: Derived from metastatic site: lung
ATCC: CRL-1973
Biosafety: 1


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