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BCRJ: | 0269 | Cell Line: | PC-3 | Tissue: | | Organ: | PROSTATA | Cell Type: | B LYMPHOCYTE | Morphology: | EPITHELIAL | Pathology: | ADENOCARCINOMA | Scientific Name: | HOMO SAPIENS | Vulgar Name: | HUMAN | Sex: | MALE | Miscelaneous Info: | 62 YEARS | Virus Succeptibility: | | Virus Resistance: | | Tumor Formation: | YES | Products: | | Dependency Isoenzymes: | | Culture Medium: | The base medium for this cell line is F-12K Medium 10% of fetal bovine serum.. | Consigner: | HERNANDES FAUSTINO DE CARVALHO
UNIVERSIDADE ESTADUAL DE CAMPINAS
LABORATORIO DE MATRIZ EXTRACELULAR | Reference: | 22363: Kaighn ME, et al. Establishment and characterization of a human prostatic carcinoma cell line (PC-3). Invest. Urol. 17: 16-23, 1979. PubMed: 447482
22470: Chen TR. Chromosome identity of human prostate cancer cell lines, PC-3 and PPC-1. Cytogenet. Cell Genet. 62: 183-184, 1993. PubMed: 8428522
26302: Ohnuki Y, et al. Chromosomal analysis of human prostatic adenocarcinoma cell lines. Cancer Res. 40: 524-534, 1980. PubMed: 7471073
32341: Sheng S, et al. Maspin acts at the cell membrane to inhibit invasion and motility of mammary and prostatic cancer cells. Proc. Natl. Acad. Sci. USA 93: 11669-11674, 1996. PubMed: 8876194
32344: Umekita Y, et al. Human prostate tumor growth in athymic mice: inhibition by androgens and stimulation by finasteride. Proc. Natl. Acad. Sci. USA 93: 11802-11807, 1996. PubMed: 8876218
32460: Carter RE, et al. Prostate-specific membrane antigen is a hydrolase with substrate and pharmacologic characteristics of a neuropeptidase. Proc. Natl. Acad. Sci. USA 93: 749-753, 1996. PubMed: 8570628
32486: Nupponen NN, et al. Genetic alterations in prostate cancer cell lines detected by comparative genomic hybridization. Cancer Genet. Cytogenet. 101: 53-57, 1998. PubMed: 9460501
32488: Geiger T, et al. Antitumor activity of a PKC-alpha antisense oligonucleotide in combination with standard chemotherapeutic agents against various human tumors transplanted into nude mice. Anticancer Drug Des. 13: 35-45, 1998. PubMed: 9474241
32916: Su ZZ, et al. Surface-epitope masking and expression cloning identifies the human prostate carcinoma tumor antigen gene PCTA-1 a member of the galectin gene family. Proc. Natl. Acad. Sci. USA 93: 7252-7257, 1996. PubMed: 8692978. | Additional Info: | The cells form clusters in soft agar and can be adapted to suspension growth;
Antigen Expression: HLA A1, A9; | ATCC: | CRL-1435 | Biosafety: | 1 |
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