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Results of Search
| BCRJ: | 0242 | | Cell Line: | U-937 | | Tissue: | HEMATOPOIETIC | | Organ: | | | Cell Type: | MONOCYTE | | Morphology: | MONOCYTE | | Pathology: | HISTIOCYTIC LYMPHOMA | | Scientific Name: | HOMO SAPIENS | | Vulgar Name: | HUMAN; CAUCASIAN | | Sex: | MALE | | Miscelaneous Info: | 37 YEARS OLD | | Virus Succeptibility: | | | Virus Resistance: | | | Tumor Formation: | | | Products: | Lysozyme; beta-2 microglobulin | | Dependency Isoenzymes: | - | | Culture Medium: | RPMI-1640 medium 90%, fetal bovine serum 10%.
Subculture procedure: maintain cultures from 1x10E5 to 1x10E6 cells/mL. | | Consigner: | Dr. C.E. Tosta, Universidade de Brasilia, Brasilia. | | Reference: | Nature 279: 328-331, 1979;
J. Immunol. 125; 463-465, 1980. | | Additional Info: | Established from malignant cells obtained from pleural effusion of
37-year caucasian male with diffuse histiocytic lymphoma. This cell line
expresses many of the monocyte-macrophage charactheristics. Cells
bears receptors for Fc and C3, avtively phagocyte antibody-coated
particles, and are induced ti differentiate into histiocytes by phorbol
esters. They are activated by supernetants from human mixed
lymphocyte cultures. | | ATCC: | CRL 1593 | | Biosafety: | 01 |
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