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BCRJ: | 0211 | Cell Line: | RAJI | Tissue: | HEMATOPOIETIC | Organ: | | Cell Type: | LYMPHOBLAST | Morphology: | LYMPHOBLAST | Pathology: | LYMPHOMA | Scientific Name: | HOMO SAPIENS | Vulgar Name: | HUMAN; NEGRO | Sex: | | Miscelaneous Info: | | Virus Succeptibility: | VESICULAR STOMATITIS; POLIOMYELITIS ( BOTH PA | Virus Resistance: | | Tumor Formation: | | Products: | | Dependency Isoenzymes: | | Culture Medium: | RPMI-1640 medium 90%, fetal bovine serum 10%.
Subculture procedure: maintain cultures from 1x10E5 to 1x10E6 cells/mL | Consigner: | Institute Pasteur, Paris, France. | Reference: | 22142: Pulvertaft JV. Cytology of Burkitt's tumour (African lymphoma). Lancet 1: 238-240, 1964. PubMed: 14086209
22169: Epstein MA, Barr YM. Characteristics and mode of growth of tissue culture strain (EB1) of human lymphoblasts from Burkitt's lymphoma. J. Natl. Cancer Inst. 34: 231-240, 1965. PubMed: 14293790
22550: Ohsugi Y, et al. Tumorigenicity of human malignant lymphoblasts: comparative study with unmanipulated nude mice, antilymphocyte serum-treated nude mice, and X- irradiated nude mice. J. Natl. Cancer Inst. 65: 715-718, 1980. PubMed: 6932523
22572: Moore PS, et al. Primary characterization of a herpesvirus agent associated with Kaposi's sarcoma. J. Virol. 70: 549-558, 1996. PubMed: 8523568
26253: Epstein MA, et al. Morphological and virological investigations on cultured Burkitt tumor lymphoblasts (strain Raji). J. Natl. Cancer Inst. 37: 547-559, 1966. PubMed: 4288580
26254: . . Trans. N.Y. Acad. Sci. 29: 61, 1966.
32395: Clark RA, et al. Tenascin supports lymphocyte rolling. J. Cell Biol. 137: 755-765, 1997. PubMed: 9151679
32448: Rich SA, et al. Purification, microresequencing, and immunolocalization of p36, a new interferon-alpha-induced protein that is associated with human lupus inclusions. J. Biol. Chem. 271: 1118-1126, 1996. PubMed: 8557639 | Additional Info: | The RAJI line of lymphoblast-like cells was established by R.Pulvertaft
in 1963 from a Burkitt lymphoma of the left maxilla of an 11 year-old
negro male. This cell line grows in suspension as single cells without
attachment to glass, and as macroscopically visible clumps containing
many hundrds of cells. Cells of RAJI line do not contain virus particles
as demonstrated by electron microscopy. | ATCC: | CCL-86 | Biosafety: | 02 |
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