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BCRJ:	0180
Cell Line:	MRC-5
Tissue:	FIBROBLAST
Organ:	LUNG
Cell Type:	FIBROBLAST
Morphology:	FIBROBLAST
Pathology:	NORMAL
Scientific Name:	HOMO SAPIENS
Vulgar Name:	HUMAN
Sex:	MALE
Miscelaneous Info:	14 WEEK-OLD
Virus Succeptibility:	POLIOVIRUS-1; HERPES SIMPLEX; VESICULAR STOMATITIS
Virus Resistance:
Tumor Formation:
Products:
Dependency Isoenzymes:	G6PD type B
Culture Medium:	Dulbecco's MEM 90%, fetal bovine serum 10%. Subculture procedure: standard trypsinization techniques. A split ratio of 1: to 1:6 is recommended.
Consigner:	Dr. Bernard Fortier, INSERM U42, Lille, France.
Reference:	Nature 227: 168-170, 1970; Nature 238: 26, 1972; Nature 239: 316, 1972.
Additional Info:	The MRC-5 cell line was derived from normal lung tissue of a 14 week-old male fetus, cells are capable of attaining 42-46 population doubling before senescence. Comparative studies showed that MRC-5 cells replicate more rapidly and are less sensitive to adverse enviromental factors than WI-38 cells. Like WI-38 cells, they are suceptible to a wide range of human viruses, and are siutable for the production of viral vaccines and senescense studies.
ATCC:	CCL 171
Biosafety:	01