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BCRJ: 0162
Cell Line: MCF-7
Tissue: EPITHELIUM
Organ: BREAST
Cell Type: EPITHELIAL
Morphology: EPITHELIAL
Pathology: ADENOCARCINOMA
Scientific Name: HOMO SAPIENS
Vulgar Name: HUMAN
Sex: FEMALE
Miscelaneous Info: CAUCASIAN, 69 YEAR OLD
Virus Succeptibility:
Virus Resistance:
Tumor Formation:
Products: Keratin
Dependency Isoenzymes:
Culture Medium: RPMI 1640 medium suplemented with 20% of fetal calf serum. Standard tripsinization techniques. Split ratio rom 1:5 to 1:8 is recommended.
Consigner: Dr. Ricardo Bretani Ludwick Institute for Cancer Research São Paulo - SP
Reference: J.Nat. Canc. Inst., 51:1409, 1973 Cancer Res., 53:5882, 1993
Additional Info: This cell line was isolated from pleural effusion from 69 year female Caucasian. Cells exhibit some features of differentiated mammary epithelium including oestradiol synthesis and formation of domes. Cells may carry B or C type retrovirus and is consiered to represent a category 2 pathogen. Cells express both wildtype and variant oestrogen receptorss as well as progesterone receptors. Restricted distribution. Only to be distributed with formal authorization of Dr. Bretani.
ATCC: HTB-22
Biosafety: 01


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