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BCRJ: | 0128 | Cell Line: | KB | Tissue: | | Organ: | MOUTH | Cell Type: | EPITHELIAL | Morphology: | EPITHELIAL | Pathology: | | Scientific Name: | HOMO SAPIENS | Vulgar Name: | HUMAN; CAUCASIAN | Sex: | MALE | Miscelaneous Info: | ADULT; HELA MARKERS | Virus Succeptibility: | POLIOVIRUS-1; ADENOVIRUS-3 | Virus Resistance: | | Tumor Formation: | | Products: | Keratin | Dependency Isoenzymes: | G6PD-A | Culture Medium: | Dulbecco's MEM 90%, fetal bovine serum 10%.
Subculture procedure: standard trypsinization techniques.
A split ratio 1:4 to 1:6 is recommended. | Consigner: | Dr. Jose Paulo Leite, Instituto Oswaldo Cruz, Rio de Janeiro. | Reference: | Proc. Exp. Biol. Med. 94: 661-, 1957;
Science 133: 1559-, 1961. | Additional Info: | Derived from a mouth carcinoma of an adult male caucasian. The
cells have been used for a variety of studies including cancer
chemotherapy screening, cell nutrition and metabolism, tumorigenicity
and virus suceptibility. The cells carry HeLa markers chromosomes. It
was one of the early sucessful attempts to isolate and serially
propagate a human cell line directly in monolayer culture. | ATCC: | CCL 17 | Biosafety: | 01 |
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