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BCRJ: 0128
Cell Line: KB
Tissue:
Organ: MOUTH
Cell Type: EPITHELIAL
Morphology: EPITHELIAL
Pathology:
Scientific Name: HOMO SAPIENS
Vulgar Name: HUMAN; CAUCASIAN
Sex: MALE
Miscelaneous Info: ADULT; HELA MARKERS
Virus Succeptibility: POLIOVIRUS-1; ADENOVIRUS-3
Virus Resistance:
Tumor Formation:
Products: Keratin
Dependency Isoenzymes: G6PD-A
Culture Medium: Dulbecco's MEM 90%, fetal bovine serum 10%. Subculture procedure: standard trypsinization techniques. A split ratio 1:4 to 1:6 is recommended.
Consigner: Dr. Jose Paulo Leite, Instituto Oswaldo Cruz, Rio de Janeiro.
Reference: Proc. Exp. Biol. Med. 94: 661-, 1957; Science 133: 1559-, 1961.
Additional Info: Derived from a mouth carcinoma of an adult male caucasian. The cells have been used for a variety of studies including cancer chemotherapy screening, cell nutrition and metabolism, tumorigenicity and virus suceptibility. The cells carry HeLa markers chromosomes. It was one of the early sucessful attempts to isolate and serially propagate a human cell line directly in monolayer culture.
ATCC: CCL 17
Biosafety: 01


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