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BCRJ:	0110
Cell Line:	HT-1080
Tissue:
Organ:	LUNG
Cell Type:	EPITHELIAL
Morphology:	EPITHELIAL-LIKE
Pathology:	SARCOMA
Scientific Name:	HOMO SAPIENS
Vulgar Name:	HUMAN
Sex:
Miscelaneous Info:	The cells contain an activated N-ras oncogene.
Virus Succeptibility:
Virus Resistance:
Tumor Formation:
Products:
Dependency Isoenzymes:
Culture Medium:	Minimum essential medium (Eagle) with 2 mM L-glutamine and Earle's BSS, 0.1 mM non-essential amino acids, and 1.0 mM sodium pyruvate, 90%; fetal bovine serum, 10%. Subculture procedure: standard trypsinization techniques. A split ratio 1:4 to 1:8 recomended.
Consigner:	Bryan Eric Strauss, Instituto do Coração Universidade de São Paulo
Reference:	Chen TR , et al. Intercellular karyotypic similarity in near-diploid cell lines of human tumor origins. Cancer Genet. Cytogenet. 10: 351-362, 1983 : Geiser AG , et al. Suppression of tumorigenicity in human cell hybrids derived from cell lines expressing different activated ras oncogenes. Cancer Res. 49: 1572-1577, 1989: Rasheed S , et al. Characterization of a newly derived human sarcoma cell line (HT-1080). Cancer 33: 1027-1033, 1974.
Additional Info:	Growth Properties: adherent
ATCC:	CCL-121
Biosafety:	01