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BCRJ: 0070
Cell Line: COS-1
Tissue:
Organ: KIDNEY
Cell Type: FIBROBLAST
Morphology: FIBROBLAST
Pathology: TRANSFECT
Scientific Name: CERCOPITHECUS AETHIOPS
Vulgar Name: MONKEY; AFRICAN GREEN MONKEY
Sex: MALE
Miscelaneous Info: ADULT
Virus Succeptibility: SV-40 (LYTIC GROWTH); SV-40 TSA209 AT 40
Virus Resistance:
Tumor Formation:
Products: T-antigen
Dependency Isoenzymes:
Culture Medium: Dulbecco's MEM 90%, fetal bovine serum 10%. Subculture procedure: standard trypsinization techniques.
Consigner: Dr. Didier Petit, Laboratoire de Virologie Moleculaire, INSERM U233, Lille, France, through Dr. Jose Paulo Leite, Instituto Oswaldo Cruz, Rio de Janeiro.
Reference: Cell 23: 175-182, 1981.
Additional Info: This cell line was derived from the CV-1 Simian cells (BCRJ CR013) by transformation with an origin-defective mutant of SV-40 wich codes for wild type T antigen. This line contains a single integrated copy of the complete early region of SV40 DNA, and is a possible host for the propagation of pure populations of recombinant SV40 virus.
ATCC: CRL 1650
Biosafety: 01


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