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BCRJ: 0028
Cell Line: 7D4
Tissue: HEMATOPOIETIC
Organ:
Cell Type: LYMPHOBLAST
Morphology: LYMPHOBLAST
Pathology: HYBRIDOMA
Scientific Name:
Vulgar Name:
Sex:
Miscelaneous Info:
Virus Succeptibility:
Virus Resistance:
Tumor Formation:
Products: Immunoglobulin; monoclonal antibody; IL-2 receptor: ab against; IgM
Dependency Isoenzymes:
Culture Medium:
Consigner: Dr. Oberdan Leo, Laboratoire d'Immunologie, Departement de biologie Molecularie, universite Libre de Bruxelles, Rhode-St-Genese, Belgium.
Reference: Proc. Nat. Acad. Sci., USA 80:5694-5698, 1983. J. Immunol., 133: 1970-75, 1984.
Additional Info: The hybridoma produces a monoclonal antibody (IgM K) that binds to interleukin-2 (IL-2) receptors on actived murine T and B cells. The antibody inhibits IL-2 driven proliferation but does not block binding of IL-2. The clone was derived by fusing Sp2/O-Ag14 cells with spleen lynphocytes from a Lewis rat immunized with the HT-2 mouse cell line. The 7D4 cell line may be distributed to scientific institutions; not to be distributed for any commercial use.
ATCC: CRL 1698
Biosafety: 01


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